Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2235Conserved hypothetical protein; Similar to PID:1652823 percent identity: 26.74; identified by sequence similarity; putative. (329 aa)    
Predicted Functional Partners:
AF_1655
Signal sequence peptidase, putative; Similar to SP:P54506 PID:1303884 GB:AL009126 percent identity: 34.46; identified by sequence similarity; putative.
     
 0.811
AF_1657
Signal sequence peptidase (spc21); Similar to PID:1149703 percent identity: 46.97; identified by sequence similarity; putative.
     
 0.811
AF_1791
Signal sequence peptidase (sec11); Similar to GB:Z47047 SP:P15367 PID:4433 PID:557828 PID:763367 percent identity: 36.30; identified by sequence similarity; putative.
     
 0.811
AF_2078
Predicted coding region AF_2078; Hypothetical protein; identified by GeneMark; putative.
     
 0.811
katG
Peroxidase / catalase (perA); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.
       0.773
AF_2234
Predicted coding region AF_2234; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_1306
Conserved hypothetical protein; Similar to PID:1652823 percent identity: 27.66; identified by sequence similarity; putative.
  
     0.598
tatA
Conserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
 
   
 0.589
AF_2232
Ferric uptake regulation protein (fur); Similar to GB:U06072 PID:508861 percent identity: 25.77; identified by sequence similarity; putative; Belongs to the Fur family.
       0.549
AF_0143
Conserved hypothetical protein; Similar to GB:L77117 PID:1592228 percent identity: 25.53; identified by sequence similarity; putative.
 
   
 0.510
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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