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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thsAThermosome, subunit alpha (thsA); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family. (545 aa)    
Predicted Functional Partners:
AF_1297
Cell division control protein 48, AAA family (cdc48-1); Similar to GB:L77117 SP:Q58556 PID:1591785 percent identity: 69.10; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily.
  
 0.891
AF_1971
Small heat shock protein (hsp20-2); Similar to SP:P19244 percent identity: 38.14; identified by sequence similarity; putative; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.883
AF_1296
Small heat shock protein (hsp20-1); Similar to GB:L77117 SP:Q57733 PID:1591008 percent identity: 52.27; identified by sequence similarity; putative; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.881
pfdB
erpK protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
  
 
 
 0.873
AF_1298
Predicted coding region AF_1298; Hypothetical protein; identified by GeneMark; putative.
      
 0.849
AF_1864
Predicted coding region AF_1864; Hypothetical protein; identified by GeneMark; putative; To A.aeolicus AQ_377.
      
 0.831
tbp
Transcription initiation factor IID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
 
 
 0.823
eif5a
Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
 
 0.815
pfdA
C-myc binding protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
   
 
 0.814
AF_0364
ATP-dependent protease La (lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity).
  
 
 0.813
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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