Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_22433-ketoacyl-CoA thiolase (fadA-3); Similar to GB:M87049 SP:P21151 GB:M59368 GB:M74164 PID:145901 percent identity: 40.83; identified by sequence similarity; putative. (414 aa)    
Predicted Functional Partners:
AF_2415
Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 0.978
AF_0964
acyl-CoA dehydrogenase (acd-6); Similar to PID:1055219 SP:P52042 percent identity: 35.77; identified by sequence similarity; putative.
  
 0.970
AF_0199
acyl-CoA dehydrogenase (acd-1); Similar to SP:P45867 PID:853760 GB:AL009126 percent identity: 35.92; identified by sequence similarity; putative.
  
 0.952
AF_0498
acyl-coA dehydrogenase (acd-3); Similar to SP:P41367 percent identity: 22.90; identified by sequence similarity; putative.
  
 0.952
AF_0991
glutaryl-CoA dehydrogenase (gcdH); Similar to GB:U69141 SP:Q92947 PID:1549327 PID:1905909 PID:2316112 percent identity: 48.68; identified by sequence similarity; putative.
  
 0.952
hmgA
3-hydroxy-3-methylglutaryl-coenzyme A reductase (mvaA); Converts HMG-CoA to mevalonate.
 
  
 0.916
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
 0.915
AF_1028
3-ketoacyl-CoA thiolase (fadA-1); Similar to GP:1742272 percent identity: 38.83; identified by sequence similarity; putative.
  
  
 
0.902
AF_2244
acyl-CoA dehydrogenase (acd-11); Similar to SP:P45857 PID:881606 PID:1303933 GB:AL009126 percent identity: 42.55; identified by sequence similarity; putative.
  
 0.897
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.875
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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