STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2246Predicted coding region AF_2246; Hypothetical protein; identified by GeneMark; putative. (177 aa)    
Predicted Functional Partners:
cdhC
acetyl-CoA decarbonylase/synthase, subunit beta (cdhC); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
  
     0.690
cdhD
acetyl-CoA decarbonylase/synthase, subunit delta (cdhD); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
  
     0.687
AF_0378
CODH nickel-insertion accessory protein (cooC-1); Similar to GB:L77117 SP:Q58233 PID:1499647 percent identity: 35.71; identified by sequence similarity; putative.
  
     0.668
AF_1685
CODH nickel-insertion accessory protein (cooC-2); Similar to GB:L77117 SP:Q58233 PID:1499647 percent identity: 47.37; identified by sequence similarity; putative.
  
     0.660
AF_2247
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58004 PID:1591292 percent identity: 37.64; identified by sequence similarity; putative.
       0.599
AF_2248
Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
       0.572
cdhA2
acetyl-CoA decarbonylase/synthase, subunit alpha (cdhA-2); Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
  
     0.528
cdhA1
acetyl-CoA decarbonylase/synthase, subunit alpha (cdhA-1); Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
  
     0.506
AF_0009
N5-methyltetrahydromethanopterin:coenzyme M methyltransferase (mtr) {Methanobacterium thermoautotro; Similar to PID:668979 GB:AE000666 percent identity: 42.09; identified by sequence similarity; putative.
  
     0.439
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.