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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2248Conserved hypothetical protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro. (77 aa)    
Predicted Functional Partners:
AF_2247
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58004 PID:1591292 percent identity: 37.64; identified by sequence similarity; putative.
 
  
 0.934
AF_1521
Conserved hypothetical protein; Removes ADP-ribose from asparatate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Catalyzes removal of a phosphate group from ADP-ribose 1''-phosphate (Appr1p), but with low efficiency.
   
 
 0.902
AF_0270
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.900
AF_2220
Predicted coding region AF_2220; Hypothetical protein; identified by GeneMark; putative.
  
 0.887
AF_1554
Thioredoxin reductase (trxB); Similar to PID:1171125 SP:P52213 percent identity: 45.21; identified by sequence similarity; putative.
  
 
 0.750
AF_0142
Cytochrome C oxidase, subunit II, putative; Similar to GB:L09121 PID:155085 SP:P98052 percent identity: 38.04; identified by sequence similarity; putative.
   
 
 0.735
rpl11
LSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
   0.715
nusA
Transcription termination-antitermination factor NusA, putative; Participates in transcription termination. Belongs to the NusA family.
   
   0.701
AF_1886
DNA-directed RNA polymerase, subunit B'' (rpoB2); Similar to SP:P15352 PID:43540 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the RNA polymerase beta chain family.
   
 
 0.678
rpoB1
DNA-directed RNA polymerase, subunit B' (rpoB1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
   
 
 0.678
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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