Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
argGArgininosuccinate synthetase (argG); Similar to GB:L77117 SP:Q60174 PID:1591132 percent identity: 62.02; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (390 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase (argH); Similar to SP:Q58201 PID:1591489 GB:L77117 SP:Q58201 PID:1591489 percent identity: 42.23; identified by sequence similarity; putative.
 
 0.999
carB
Carbamoyl-phosphate synthase, large (or ammonia) subunit (carB); Similar to PID:1001613 PID:1001668 percent identity: 65.08; identified by sequence similarity; putative.
 
 
 0.997
argF
Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.996
carA
Carbamoyl-phosphate synthase, small (or glutamine) subunit (carA); Similar to GB:L77117 SP:Q58425 PID:1591677 percent identity: 55.17; identified by sequence similarity; putative; Belongs to the CarA family.
  
 
 0.968
argB
Acetylglutamate kinase (argB); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.965
argC
N-acetyl-gamma-glutamyl-phosphate reductase (argC); Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.965
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.952
AF_0522
Acetylornithine deacetylase (argE); Similar to GB:L77117 PID:1592133 percent identity: 29.58; identified by sequence similarity; putative.
  
 0.948
argD
Acetylornithine aminotransferase (argD-1); Similar to GB:L77117 SP:Q58131 PID:1591438 percent identity: 48.28; identified by sequence similarity; putative; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.938
AF_1439
Asparagine synthetase (asnB); Similar to GB:L77117 SP:Q58516 PID:1591755 percent identity: 36.88; identified by sequence similarity; putative.
   
 0.934
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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