Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2264Conserved hypothetical protein; Similar to GP:1787662 percent identity: 39.67; identified by sequence similarity; putative; Belongs to the thioesterase PaaI family. (154 aa)    
Predicted Functional Partners:
AF_2013
Coenzyme F390 synthetase (ftsA-3); Similar to PID:1050923 GB:AE000666 percent identity: 30.41; identified by sequence similarity; putative.
 
 
 0.934
AF_1671
Coenzyme F390 synthetase (ftsA-2); Similar to PID:1050923 GB:AE000666 percent identity: 29.43; identified by sequence similarity; putative.
 
 
 0.932
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
  
 0.545
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
  
 0.512
AF_1289
Conserved hypothetical protein; May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone (By similarity).
      0.469
AF_0675
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase (todF); Similar to GB:M64080 SP:P23133 GB:U18304 PID:151222 percent identity: 26.35; identified by sequence similarity; putative.
    
 0.443
AF_1563
Conserved hypothetical protein; Similar to SP:P29368 GB:M38048 SP:Q99390 PID:151837 PID:42626 percent identity: 33.94; identified by sequence similarity; putative.
    
 0.443
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (16%) [HD]