Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_2269Nucleotide-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (254 aa)    
Predicted Functional Partners:
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
  
 
 0.838
hypA
Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
   0.796
AF_1830
F420H2:quinone oxidoreductase, 45 kDa subunit (nuoD); Similar to PIR:S45666 percent identity: 80.00; identified by sequence similarity; putative.
    
 0.629
AF_1829
F420H2:quinone oxidoreductase, 39.7 kDa subunit, putative; Similar to SP:P15602 percent identity: 44.09; identified by sequence similarity; putative.
    
 0.581
AF_2270
Predicted coding region AF_2270; Hypothetical protein; identified by GeneMark; putative.
       0.556
AF_2377
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58000 PID:1591287 percent identity: 34.83; identified by sequence similarity; putative.
 
  
 0.489
pol
DNA polymerase B1 (polB); Similar to PID:807830 percent identity: 45.13; identified by sequence similarity; putative.
   
 0.468
AF_2378
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58000 PID:1591287 percent identity: 30.00; identified by sequence similarity; putative.
  
  
 0.445
AF_0595
Polysaccharide biosynthesis protein, putative; Similar to GB:L77117 PID:1591720 percent identity: 24.05; identified by sequence similarity; putative.
  
  
 0.442
AF_1247
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
 
  
 0.439
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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