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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2269Nucleotide-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (254 aa)    
Predicted Functional Partners:
hypA
Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
 
 0.779
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
  
 
 0.737
AF_1830
F420H2:quinone oxidoreductase, 45 kDa subunit (nuoD); Similar to PIR:S45666 percent identity: 80.00; identified by sequence similarity; putative.
    
 0.709
AF_1829
F420H2:quinone oxidoreductase, 39.7 kDa subunit, putative; Similar to SP:P15602 percent identity: 44.09; identified by sequence similarity; putative.
  
 
 0.675
AF_2270
Predicted coding region AF_2270; Hypothetical protein; identified by GeneMark; putative.
       0.556
AF_1247
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
 
  
 0.460
AF_2377
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58000 PID:1591287 percent identity: 34.83; identified by sequence similarity; putative.
 
  
 0.451
AF_0595
Polysaccharide biosynthesis protein, putative; Similar to GB:L77117 PID:1591720 percent identity: 24.05; identified by sequence similarity; putative.
  
  
 0.450
AF_2272
Predicted coding region AF_2272; Hypothetical protein; identified by GeneMark; putative.
 
     0.419
rfcS
Activator 1, replication factor C, 35 KD subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. Belongs to the activator 1 small subunits family. RfcS subfamily.
  
   0.412
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.