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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2278Pyruvate formate-lyase activating enzyme (act-4); Similar to GB:L77117 SP:Q58218 PID:1499631 percent identity: 42.46; identified by sequence similarity; putative. (330 aa)    
Predicted Functional Partners:
AF_2310
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57846 PID:1591108 percent identity: 47.01; identified by sequence similarity; putative; Belongs to the MEMO1 family.
     0.904
AF_1969
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58220 PID:1592310 percent identity: 55.84; identified by sequence similarity; putative.
     0.888
AF_1449
Pyruvate formate-lyase 2 (pflD); Similar to SP:P32674 GB:U00006 PID:396298 GB:U00096 PID:1790388 percent identity: 37.81; identified by sequence similarity; putative.
  
  
 0.837
AF_0117
Pyruvate formate-lyase activating enzyme (act-1); Similar to GB:L77117 PID:1591858 percent identity: 25.47; identified by sequence similarity; putative.
  
   
 0.804
AF_2279
Conserved hypothetical protein; Similar to GB:L77117 PID:1500516 percent identity: 35.71; identified by sequence similarity; putative.
       0.773
AF_2280
Conserved hypothetical protein; Similar to GB:L77117 PID:1500516 percent identity: 37.66; identified by sequence similarity; putative.
       0.773
AF_2281
Aldehyde ferredoxin oxidoreductase (aor-4); Similar to PID:736274 percent identity: 52.97; identified by sequence similarity; putative.
       0.578
afung
DNA polymerase, bacteriophage-type; Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA.
       0.570
AF_2276
Conserved hypothetical protein; Similar to GB:L77117 PID:1591555 percent identity: 39.31; identified by sequence similarity; putative.
       0.560
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
  
  
 0.545
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.