Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fniCarotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (317 aa)    
Predicted Functional Partners:
AF_2286
Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family.
  
 
 0.992
AF_2288
Acetylglutamate kinase, putative; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
 
  
 0.992
mvk
Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
  
 0.989
hmgA
3-hydroxy-3-methylglutaryl-coenzyme A reductase (mvaA); Converts HMG-CoA to mevalonate.
   
 0.965
AF_1417
Aspartate aminotransferase (aspC); Similar to GB:L77117 PID:1591623 percent identity: 49.29; identified by sequence similarity; putative.
  
 0.794
rps2
SSU ribosomal protein S2P (rps2P); Similar to GB:L77117 SP:P54109 PID:1591644 percent identity: 58.33; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.702
gltX
glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.700
AF_0806
L-lactate permease (lctP); Similar to SP:P33231 GB:L13970 PID:404693 PID:466741 GB:U00096 percent identity: 31.70; identified by sequence similarity; putative.
  
  
 0.691
eno
Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.680
AF_0274
Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.
  
 
 0.669
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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