| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_2286 | AF_2288 | AF_2286 | AF_2288 | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | Acetylglutamate kinase, putative; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | 0.977 |
| AF_2286 | AF_2415 | AF_2286 | AF_2415 | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | 0.539 |
| AF_2286 | fni | AF_2286 | AF_2287 | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | Carotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.988 |
| AF_2286 | hmgA | AF_2286 | AF_1736 | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase (mvaA); Converts HMG-CoA to mevalonate. | 0.551 |
| AF_2286 | mvk | AF_2286 | AF_2289 | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.850 |
| AF_2288 | AF_2286 | AF_2288 | AF_2286 | Acetylglutamate kinase, putative; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | 0.977 |
| AF_2288 | fni | AF_2288 | AF_2287 | Acetylglutamate kinase, putative; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Carotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.975 |
| AF_2288 | mvk | AF_2288 | AF_2289 | Acetylglutamate kinase, putative; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.902 |
| AF_2415 | AF_2286 | AF_2415 | AF_2286 | Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | 0.539 |
| AF_2415 | fni | AF_2415 | AF_2287 | Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | Carotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.457 |
| AF_2415 | hmgA | AF_2415 | AF_1736 | Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase (mvaA); Converts HMG-CoA to mevalonate. | 0.990 |
| AF_2415 | mvk | AF_2415 | AF_2289 | Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.709 |
| carS | mvk | AF_1740 | AF_2289 | Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. Can use CTP or dCTP, but not ATP, GTP or TTP; Belongs to the CDP-archaeol synthase family. | Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.758 |
| carS | tpiA | AF_1740 | AF_1304 | Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. Can use CTP or dCTP, but not ATP, GTP or TTP; Belongs to the CDP-archaeol synthase family. | Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.838 |
| eif2g | mvk | AF_0592 | AF_2289 | Translation initiation factor eIF-2, subunit gamma (eif2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.691 |
| eif2g | rnz | AF_0592 | AF_0939 | Translation initiation factor eIF-2, subunit gamma (eif2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.593 |
| eif2g | sepS | AF_0592 | AF_0110 | Translation initiation factor eIF-2, subunit gamma (eif2G); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | Conserved hypothetical protein; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys); Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily. | 0.615 |
| fni | AF_2286 | AF_2287 | AF_2286 | Carotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Geranylgeranyl diphosphate synthase, type I; Similar to PID:913252 SP:Q53479 percent identity: 42.68; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | 0.988 |
| fni | AF_2288 | AF_2287 | AF_2288 | Carotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Acetylglutamate kinase, putative; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | 0.975 |
| fni | AF_2415 | AF_2287 | AF_2415 | Carotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family. | 0.457 |
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