Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_2299Predicted coding region AF_2299; Hypothetical protein; identified by GeneMark; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (344 aa)    
Predicted Functional Partners:
dys2
Deoxyhypusine synthase (dys1-2); Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
  
    0.783
AF_1420
Membrane protein; Similar to GB:L77117 SP:Q58237 PID:1591514 percent identity: 51.83; identified by sequence similarity; putative.
   
 
 0.777
AF_2298
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58249 PID:1591526 percent identity: 32.16; identified by sequence similarity; putative; Belongs to the eukaryotic-type primase small subunit family.
  
    0.746
AF_1143
CDP-diacylglycerol--glycerol-3-phosphate-3- phosphatidyltransferase (pgsA-1); Similar to GB:L42023 SP:P44528 PID:1003150 PID:1222037 PID:1204382 percent identity: 27.01; identified by sequence similarity; putative.
  
     0.686
AF_2430
lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative.
 
    0.652
asd-2
Phosphatidylserine decarboxylase (psd2); Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer).
   
 
 0.641
pdaD1
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57764 PID:1591036 percent identity: 38.26; identified by sequence similarity; putative; Belongs to the PdaD family.
       0.594
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.589
AF_1794
Myo-inositol-1-phosphate synthase (ino1); Similar to SP:P11986 PID:1015571 PID:854544 percent identity: 32.24; identified by sequence similarity; putative.
 
   
 0.538
AF_2251
Competence-damage protein, putative; Similar to percent identity: 28.02; identified by sequence similarity; putative; Belongs to the CinA family.
  
  
 0.534
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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