Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2318Conserved hypothetical protein; Similar to GB:L77117 SP:Q57666 PID:1498989 percent identity: 38.13; identified by sequence similarity; putative. (145 aa)    
Predicted Functional Partners:
rps3ae
SSU ribosomal protein S3AE (rps3AE); Similar to GB:L77117 SP:P54059 PID:1499819 percent identity: 39.42; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.929
rpl15e
LSU ribosomal protein L15E (rpl15E); Similar to GB:L77117 SP:P54060 PID:1591645 percent identity: 70.31; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL15 family.
 
     0.922
rnp3
Conserved hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
       0.906
AF_1395
Conserved hypothetical protein; Similar to GB:L77117 PID:1592047 percent identity: 45.41; identified by sequence similarity; putative; In the N-terminal section; belongs to the UPF0200 family.
  
   
 0.887
rrp4
Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (Probable); Belongs to the RRP4 family.
 
     0.704
pfdB
erpK protein, putative; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
 
     0.689
rpl37ae
LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA.
 
     0.680
AF_0491
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family.
     
 0.673
rrp41
Ribonuclease PH (rph); Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (Probable).
     
 0.673
rrp42
Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
     
 0.673
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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