close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcm2L-isoaspartyl protein carboxyl methyltransferase (pcm-2); Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins (By similarity). (219 aa)    
Predicted Functional Partners:
AF_2321
Conserved hypothetical protein; Similar to GB:L77117 PID:1591756 percent identity: 40.12; identified by sequence similarity; putative.
       0.844
cobS2
Cobalamin (5'-phosphate) synthase (cobS-2); Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate (By similarity); Belongs to the CobS family.
       0.800
surE
surE stationary-phase survival protein (surE); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
  
 0.638
rnp3
Conserved hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
  
    0.592
taw1
Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
  
    0.571
rps3ae
SSU ribosomal protein S3AE (rps3AE); Similar to GB:L77117 SP:P54059 PID:1499819 percent identity: 39.42; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS1 family.
       0.560
AF_2318
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57666 PID:1498989 percent identity: 38.13; identified by sequence similarity; putative.
       0.532
rpl15e
LSU ribosomal protein L15E (rpl15E); Similar to GB:L77117 SP:P54060 PID:1591645 percent identity: 70.31; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL15 family.
       0.532
AF_1827
F420H2:quinone oxidoreductase, 43.2 kDa subunit, putative; Similar to PID:882405 SP:P50973 percent identity: 26.99; identified by sequence similarity; putative.
  
    0.456
AF_2316
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58036 PID:1591330 percent identity: 49.40; identified by sequence similarity; putative.
       0.440
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (24%) [HD]