Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AF_2333Conserved hypothetical protein; Similar to GB:L77117 PID:1591952 percent identity: 45.50; identified by sequence similarity; putative. (380 aa)    
Predicted Functional Partners:
AF_0055
Conserved hypothetical protein; Similar to GB:L77117 PID:1592056 percent identity: 48.00; identified by sequence similarity; putative; Belongs to the UPF0107 family.
 
 
 0.999
mvk
Mevalonate kinase (mvk); Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
  0.913
speE
Spermidine synthase (speE); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
       0.773
AF_0053
Conserved hypothetical protein; Similar to PID:1001613 percent identity: 41.63; identified by sequence similarity; putative.
       0.681
ubiX
Phenylacrylic acid decarboxylase (pad1); Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
     0.667
AF_2049
Conserved hypothetical protein; Similar to GB:L77117 PID:1591954 percent identity: 31.36; identified by sequence similarity; putative.
 
     0.623
cobD
Cobalamin biosynthesis protein (cbiB); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.612
AF_2335
Conserved hypothetical protein; Similar to GP:1200033 percent identity: 39.64; identified by sequence similarity; putative.
       0.565
AF_2200
Mutator protein MutT, putative; Similar to GB:L77117 PID:1500003 percent identity: 41.98; identified by sequence similarity; putative.
       0.563
AF_1423
Conserved hypothetical protein; Similar to GP:1561567 percent identity: 36.39; identified by sequence similarity; putative.
       0.545
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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