Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2364ABC transporter, ATP-binding protein; Similar to PID:747641 GB:AE000666 percent identity: 52.65; identified by sequence similarity; putative. (254 aa)    
Predicted Functional Partners:
AF_2365
Conserved hypothetical protein; Similar to PID:726070 GB:AE000666 percent identity: 46.36; identified by sequence similarity; putative; Belongs to the UPF0051 (ycf24) family.
 
 0.999
iscU1
nifU protein (nifU-1); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family.
  
  
 0.869
AF_0565
nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.
  
  
 0.869
serS
seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
       0.618
pol
DNA polymerase B1 (polB); Similar to PID:807830 percent identity: 45.13; identified by sequence similarity; putative.
     
 0.617
AF_2363
Conserved hypothetical protein; Similar to GB:L77117 PID:1500295 percent identity: 54.77; identified by sequence similarity; putative.
       0.544
AF_1536
Glutaredoxin (grx-1); Similar to PID:1652611 percent identity: 34.29; identified by sequence similarity; putative.
 
  
 0.488
AF_0632
nifU protein (nifU-3); Similar to PID:1653754 percent identity: 47.37; identified by sequence similarity; putative.
  
  
 0.434
AF_0869
Conserved hypothetical protein; Similar to GP:1402531 percent identity: 48.31; identified by sequence similarity; putative; Belongs to the UPF0145 family.
  
  
 0.433
AF_2308
Arsenite transport protein (arsB); Similar to SP:P08691 GB:J02591 SP:P37310 GB:X80057 PID:151858 percent identity: 24.66; identified by sequence similarity; putative.
     
 0.427
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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