STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2399rRNA methylase, putative; Similar to GB:L43967 PID:1045943 SP:P47494 percent identity: 36.36; identified by sequence similarity; putative; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (224 aa)    
Predicted Functional Partners:
AF_2400
Predicted coding region AF_2400; Hypothetical protein; identified by GeneMark; putative.
       0.703
AF_2401
Predicted coding region AF_2401; Hypothetical protein; identified by GeneMark; putative.
       0.703
AF_2402
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58536 PID:1591770 percent identity: 51.68; identified by sequence similarity; putative.
       0.669
srp54
Signal recognition particle, subunit SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (Probable). Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
    0.653
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.553
ftsY
Signal recognition particle receptor (dpa); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
  
     0.535
cysS
cysteinyl-tRNA synthetase (cysS); Similar to GB:D26185 SP:Q06752 GB:L14580 GB:X73989 PID:289284 percent identity: 46.12; identified by sequence similarity; putative.
     0.533
AF_2363
Conserved hypothetical protein; Similar to GB:L77117 PID:1500295 percent identity: 54.77; identified by sequence similarity; putative.
       0.526
taw1
Conserved hypothetical protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
 
     0.510
AF_1364
GTP-binding protein; Similar to GB:L77117 PID:1591973 percent identity: 57.47; identified by sequence similarity; putative.
 
     0.495
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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