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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2402Conserved hypothetical protein; Similar to GB:L77117 SP:Q58536 PID:1591770 percent identity: 51.68; identified by sequence similarity; putative. (517 aa)    
Predicted Functional Partners:
AF_2400
Predicted coding region AF_2400; Hypothetical protein; identified by GeneMark; putative.
       0.737
AF_2401
Predicted coding region AF_2401; Hypothetical protein; identified by GeneMark; putative.
       0.737
tuf
Translation elongation factor EF-1, subunit alpha (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
    
 
 0.704
rsmA
Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.704
rtcA
Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
   
  
 0.692
AF_0058
Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family.
  
    0.670
AF_2399
rRNA methylase, putative; Similar to GB:L43967 PID:1045943 SP:P47494 percent identity: 36.36; identified by sequence similarity; putative; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.669
AF_0860
Predicted coding region AF_0860; Hypothetical protein; identified by GeneMark; putative.
   
  
 0.640
AF_1972
Conserved hypothetical protein; Similar to GB:L77117 PID:1500551 percent identity: 30.07; identified by sequence similarity; putative.
   
  
 0.640
AF_2146
GTP-binding protein; Similar to GB:L77117 PID:1591967 percent identity: 65.91; identified by sequence similarity; putative.
  
    0.638
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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