Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_2408Conserved hypothetical protein; Similar to GP:1881347 percent identity: 28.89; identified by sequence similarity; putative. (150 aa)    
Predicted Functional Partners:
AF_0270
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.620
AF_2409
Iron-sulfur cluster binding protein; Similar to percent identity: 28.21; identified by sequence similarity; putative.
     
 0.588
ribH
Riboflavin synthase, subunit beta (ribE); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
    0.476
AF_2127
Transcriptional regulatory protein, LysR family; Similar to GB:L77117 SP:Q57748 PID:1591023 percent identity: 30.80; identified by sequence similarity; putative.
     
 0.473
AF_2413
Coenzyme PQQ synthesis protein (pqqE); Similar to SP:P27507 PID:809708 percent identity: 30.47; identified by sequence similarity; putative.
 
   
 0.472
AF_2410
Predicted coding region AF_2410; Hypothetical protein; identified by GeneMark; putative.
       0.467
AF_2411
Conserved hypothetical protein; Similar to GP:1694883 percent identity: 32.55; identified by sequence similarity; putative.
  
  
 0.457
AF_0164
Ferredoxin-nitrite reductase (nirA); Similar to PID:1001216 PID:1001208 percent identity: 29.72; identified by sequence similarity; putative.
   
    0.441
AF_2220
Predicted coding region AF_2220; Hypothetical protein; identified by GeneMark; putative.
 
   
 0.435
AF_2407
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58298 PID:1591566 percent identity: 35.33; identified by sequence similarity; putative.
       0.434
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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