close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_2413Coenzyme PQQ synthesis protein (pqqE); Similar to SP:P27507 PID:809708 percent identity: 30.47; identified by sequence similarity; putative. (375 aa)    
Predicted Functional Partners:
AF_1125
Heme biosynthesis protein (nirJ-1); Similar to GP:1783281 percent identity: 38.73; identified by sequence similarity; putative.
 
  
0.949
ctaB
Cytochrome C oxidase folding protein (coxD); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
    
  0.900
thiC
Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
    0.783
AF_2411
Conserved hypothetical protein; Similar to GP:1694883 percent identity: 32.55; identified by sequence similarity; putative.
       0.651
AF_1594
Heme biosynthesis protein (nirH); Similar to GP:1783280 percent identity: 25.20; identified by sequence similarity; putative.
 
  
 0.626
AF_2415
Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family.
       0.578
AF_2414
Conserved hypothetical protein; Similar to GB:L77117 PID:1592176 percent identity: 52.42; identified by sequence similarity; putative.
       0.576
AF_2410
Predicted coding region AF_2410; Hypothetical protein; identified by GeneMark; putative.
       0.533
AF_2409
Iron-sulfur cluster binding protein; Similar to percent identity: 28.21; identified by sequence similarity; putative.
  
    0.517
AF_0144
Cytochrome C oxidase, subunit II (cbaB); Similar to GB:L09121 PID:155085 SP:P98052 percent identity: 34.18; identified by sequence similarity; putative.
 
  
 0.501
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.