Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
BB_0032Conserved hypothetical protein. (490 aa)    
Predicted Functional Partners:
lepB
Signal peptidase I; Identified by match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
 
     0.912
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.884
BB_0512
Conserved hypothetical protein.
 
    0.789
BB_0170
Conserved hypothetical protein.
 
     0.788
lepB-2
Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
 
     0.780
BB_0838
Conserved hypothetical protein.
  
     0.774
BB_0455
DNA polymerase III, delta subunit superfamily; Identified by match to protein family HMM PF06144.
  
     0.770
BB_0592
Caax amino protease family; Identified by match to protein family HMM PF02517.
  
    0.766
BB_0058
Tetratricopeptide repeat domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719.
 
     0.764
BB_0072
Membrane protein, putative.
  
     0.764
Your Current Organism:
Borreliella burgdorferi
NCBI taxonomy Id: 224326
Other names: B. burgdorferi B31, Borrelia burgdorferi B31, Borrelia burgdorferi str. B31, Borreliella burgdorferi B31
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