Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
BB_0141Membrane fusion protein; Identified by match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (317 aa)    
Predicted Functional Partners:
BB_0142
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
 
 0.999
BB_0080
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
 
 0.894
lepB-2
Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
  
  
 0.683
polA
DNA polymerase I superfamily; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.682
BB_0806
Lipoprotein, putative.
  
  
 0.676
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
   0.656
BB_0250
DedA protein; Required for proper cell division and envelope integrity. Belongs to the DedA family.
  
 
 0.624
lepB-3
Signal peptidase I; Identified by match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
   
  
 0.623
lepB
Signal peptidase I; Identified by match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
   
  
 0.621
BB_0143
Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.614
Your Current Organism:
Borreliella burgdorferi
NCBI taxonomy Id: 224326
Other names: B. burgdorferi B31, Borrelia burgdorferi B31, Borrelia burgdorferi str. B31, Borreliella burgdorferi B31
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