Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BB_0219Metal cation transporter, zinc (Zn2+)-iron (Fe2+) permease (ZIP) family; Identified by match to protein family HMM PF02535. (273 aa)    
Predicted Functional Partners:
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity).
     
 0.849
BB_0221
Flagellar motor switch protein; Identified by match to protein family HMM PF01706.
       0.834
pgl
6-phosphogluconolactonase (6PGL); Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
       0.834
sod
Superoxide dismutase [Mn] (General stress protein 24)(GSP24); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.725
polA
DNA polymerase I superfamily; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.678
bosR
Borrelia oxidative stress regulator protein BosR; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
  
  
 0.564
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
    
 0.499
BB_0584
Conserved hypothetical integral membrane protein; Identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797.
   
 
 0.451
BB_0225
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
   
   0.445
BB_0625
N-acetylmuramoyl-L-alanine amidase, putative; Identified by match to protein family HMM PF01476; match to protein family HMM PF01520.
     
 0.442
Your Current Organism:
Borreliella burgdorferi
NCBI taxonomy Id: 224326
Other names: B. burgdorferi B31, Borrelia burgdorferi B31, Borrelia burgdorferi str. B31, Borreliella burgdorferi B31
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