Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hbbSmall DNA-binding protein Hbb; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (108 aa)    
Predicted Functional Partners:
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.984
BB_0231
Identified by match to protein family HMM PF04519.
       0.893
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.869
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
    
 
 0.816
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.802
BB_0234
Conserved hypothetical integral membrane protein.
       0.785
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.774
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
  
 0.744
rpmE
Ribosomal protein L31; Identified by match to protein family HMM PF01197; match to protein family HMM TIGR00105.
  
  
 0.743
BB_0236
Tetratricopeptide repeat domain protein; Identified by match to protein family HMM PF01436.
       0.741
Your Current Organism:
Borreliella burgdorferi
NCBI taxonomy Id: 224326
Other names: B. burgdorferi B31, Borrelia burgdorferi B31, Borrelia burgdorferi str. B31, Borreliella burgdorferi B31
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