STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (354 aa)    
Predicted Functional Partners:
mvaD
Diphosphomevalonate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240.
 
  
 0.999
mvk
Mevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549.
 
  
 0.993
BB_0683
hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835.
 
  
 0.992
BB_0687
Phosphomevalonate kinase, putative; Identified by match to protein family HMM PF00288.
 
   
 0.973
BB_0685
hydroxymethylglutaryl-CoA reductase, degradative; Converts HMG-CoA to mevalonate.
    
 0.970
BB_0604
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.951
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
     
 0.878
BB_0104
Periplasmic serine protease DO; Identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037.
    
 0.673
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.659
BB_0314
Octaprenyl-diphosphate synthase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
  
  
 0.628
Your Current Organism:
Borreliella burgdorferi
NCBI taxonomy Id: 224326
Other names: B. burgdorferi B31, Borrelia burgdorferi B31, Borrelia burgdorferi str. B31, Borreliella burgdorferi B31
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