Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpoSRNA polymerase sigma factor (rpoS); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (266 aa)    
Predicted Functional Partners:
bosR
Borrelia oxidative stress regulator protein BosR; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
  
 
 0.964
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.927
rpoN
RNA polymerase sigma-54 factor; Identified by match to protein family HMM PF00309; match to protein family HMM PF04552; match to protein family HMM PF04963; match to protein family HMM TIGR02395.
   
  
 0.921
csrA
Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
      
 0.920
rpoZ
DNA-directed RNA polymerase, omega subunit; Identified by match to protein family HMM TIGR00690.
   
 
 0.899
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.894
BB_0806
Lipoprotein, putative.
   
 
 0.893
BB_0240
Glycerol uptake facilitator; Identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.845
napA
Neutrophil activating protein A (napA); Identified by match to protein family HMM PF00210; Belongs to the Dps family.
   
  
 0.841
BB_0768
Pyridoxal kinase; Belongs to the pyridoxine kinase family.
     
 0.837
Your Current Organism:
Borreliella burgdorferi
NCBI taxonomy Id: 224326
Other names: B. burgdorferi B31, Borrelia burgdorferi B31, Borrelia burgdorferi str. B31, Borreliella burgdorferi B31
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