node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AND88271.1 | hoxX | AAV28_11015 | AAV28_32220 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | 0.846 |
AND88271.1 | nusB | AAV28_11015 | AAV28_22500 | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.558 |
AND91922.1 | hoxX | AAV28_32210 | AAV28_32220 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | 0.809 |
AND91922.1 | hupK | AAV28_32210 | AAV28_32255 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HupK family. | 0.942 |
AND91922.1 | hypA2 | AAV28_32210 | AAV28_32250 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.796 |
AND91922.1 | hypB | AAV28_32210 | AAV28_32245 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel incorporation protein HypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | 0.835 |
AND91922.1 | hypC | AAV28_32210 | AAV28_32235 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.813 |
AND91922.1 | hypD2 | AAV28_32210 | AAV28_32230 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase formation protein HupD; Involved in the maturation of [NiFe] hydrogenases. Involved in the biosynthesis of the Fe(CN)(2)CO cofactor. | 0.797 |
AND91922.1 | hypE-2 | AAV28_32210 | AAV28_32225 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase; Involved in the maturation of [NiFe] hydrogenases. Along with HypF, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypE catalyzes the ATP-dependent dehydration of the carboxamido group attached to its C-terminal cysteine to a cyano group. | 0.797 |
AND91922.1 | hypF-2 | AAV28_32210 | AAV28_32240 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyltransferase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.799 |
hoxX | AND88271.1 | AAV28_32220 | AAV28_11015 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.846 |
hoxX | AND91922.1 | AAV28_32220 | AAV28_32210 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.809 |
hoxX | hupK | AAV28_32220 | AAV28_32255 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HupK family. | 0.837 |
hoxX | hypA2 | AAV28_32220 | AAV28_32250 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.833 |
hoxX | hypB | AAV28_32220 | AAV28_32245 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Hydrogenase nickel incorporation protein HypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. | 0.821 |
hoxX | hypC | AAV28_32220 | AAV28_32235 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.809 |
hoxX | hypD2 | AAV28_32220 | AAV28_32230 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Hydrogenase formation protein HupD; Involved in the maturation of [NiFe] hydrogenases. Involved in the biosynthesis of the Fe(CN)(2)CO cofactor. | 0.811 |
hoxX | hypE-2 | AAV28_32220 | AAV28_32225 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Hydrogenase; Involved in the maturation of [NiFe] hydrogenases. Along with HypF, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypE catalyzes the ATP-dependent dehydration of the carboxamido group attached to its C-terminal cysteine to a cyano group. | 0.815 |
hoxX | hypF-2 | AAV28_32220 | AAV28_32240 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Carbamoyltransferase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.860 |
hoxX | nusB | AAV28_32220 | AAV28_22500 | Hydrogenase maturation protein; Involved in the post-translational processing of the hydrogenase large subunit. | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.788 |