node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AND86671.1 | mtnA | AAV28_01635 | AAV28_01645 | Aminoacyl carrier protein 1; Aminoacyl carrier protein. Can be charged with L-glycine via the formation of a thioester bond between the amino acid and the 4'- phosphopantetheinyl prosthetic group, catalyzed by the bll0957 ligase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.410 |
AND86671.1 | mtnP | AAV28_01635 | AAV28_01640 | Aminoacyl carrier protein 1; Aminoacyl carrier protein. Can be charged with L-glycine via the formation of a thioester bond between the amino acid and the 4'- phosphopantetheinyl prosthetic group, catalyzed by the bll0957 ligase. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.461 |
AND86671.1 | tal | AAV28_01635 | AAV28_31390 | Aminoacyl carrier protein 1; Aminoacyl carrier protein. Can be charged with L-glycine via the formation of a thioester bond between the amino acid and the 4'- phosphopantetheinyl prosthetic group, catalyzed by the bll0957 ligase. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.512 |
AND89968.1 | mtnP | AAV28_20820 | AAV28_01640 | Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.475 |
AND91358.1 | guaA | AAV28_28805 | AAV28_16965 | Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.889 |
AND91358.1 | guaB | AAV28_28805 | AAV28_16875 | Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.403 |
AND91358.1 | mtnA | AAV28_28805 | AAV28_01645 | Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.425 |
AND91358.1 | mtnP | AAV28_28805 | AAV28_01640 | Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.502 |
apt | gpt | AAV28_09375 | AAV28_25530 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.944 |
apt | guaA | AAV28_09375 | AAV28_16965 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.988 |
apt | guaB | AAV28_09375 | AAV28_16875 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.431 |
apt | mtnA | AAV28_09375 | AAV28_01645 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.435 |
apt | mtnP | AAV28_09375 | AAV28_01640 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.922 |
gpt | apt | AAV28_25530 | AAV28_09375 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.944 |
gpt | guaA | AAV28_25530 | AAV28_16965 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.988 |
gpt | guaB | AAV28_25530 | AAV28_16875 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.937 |
gpt | mtnA | AAV28_25530 | AAV28_01645 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.425 |
gpt | mtnP | AAV28_25530 | AAV28_01640 | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.502 |
guaA | AND91358.1 | AAV28_16965 | AAV28_28805 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.889 |
guaA | apt | AAV28_16965 | AAV28_09375 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.988 |