node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gnd | hisI | bbp_101 | bbp_100 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.686 |
gnd | metG | bbp_101 | bbp_103 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.607 |
gnd | pgk | bbp_101 | bbp_400 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. | 0.535 |
gnd | pta | bbp_101 | bbp_165 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. | 0.535 |
gnd | rpe | bbp_101 | bbp_479 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. | 0.942 |
gnd | rpiA | bbp_101 | bbp_371 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.925 |
gnd | talA | bbp_101 | bbp_087 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.877 |
gnd | tktB | bbp_101 | bbp_088 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.895 |
gnd | ybhE | bbp_101 | bbp_274 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Conserved hypothetical protein; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. | 0.923 |
gnd | zwf | bbp_101 | bbp_298 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.975 |
hisI | gnd | bbp_100 | bbp_101 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.686 |
hisI | metG | bbp_100 | bbp_103 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.612 |
hisI | pgk | bbp_100 | bbp_400 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. | 0.455 |
hisI | pta | bbp_100 | bbp_165 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. | 0.588 |
hisI | rpe | bbp_100 | bbp_479 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. | 0.457 |
metG | gnd | bbp_103 | bbp_101 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. | 0.607 |
metG | hisI | bbp_103 | bbp_100 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.612 |
metG | pgk | bbp_103 | bbp_400 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. | 0.500 |
metG | pta | bbp_103 | bbp_165 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family. | 0.714 |
metG | rpe | bbp_103 | bbp_479 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family. | 0.441 |