| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cvpA | folC | bbp_158 | bbp_157 | Colicin V production-like protein; COG1286. | Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.692 |
| cvpA | hisI | bbp_158 | bbp_100 | Colicin V production-like protein; COG1286. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.414 |
| cvpA | metG | bbp_158 | bbp_103 | Colicin V production-like protein; COG1286. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.442 |
| cvpA | pheT | bbp_158 | bbp_124 | Colicin V production-like protein; COG1286. | COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.442 |
| cvpA | purH | bbp_158 | bbp_032 | Colicin V production-like protein; COG1286. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COG0138; bifunctional purine biosynthesis protein PurH; AICAR transformylase; inosinicase; IMP synthetase; ATIC. | 0.456 |
| cvpA | ygjT | bbp_158 | bbp_156 | Colicin V production-like protein; COG1286. | Putative transport protein; COG0861. | 0.463 |
| folC | cvpA | bbp_157 | bbp_158 | Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Colicin V production-like protein; COG1286. | 0.692 |
| folC | ygjT | bbp_157 | bbp_156 | Folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Putative transport protein; COG0861. | 0.553 |
| hisI | cvpA | bbp_100 | bbp_158 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Colicin V production-like protein; COG1286. | 0.414 |
| hisI | metG | bbp_100 | bbp_103 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.612 |
| hisI | pheT | bbp_100 | bbp_124 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.429 |
| hisI | purH | bbp_100 | bbp_032 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COG0138; bifunctional purine biosynthesis protein PurH; AICAR transformylase; inosinicase; IMP synthetase; ATIC. | 0.689 |
| hisI | ygjT | bbp_100 | bbp_156 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Putative transport protein; COG0861. | 0.420 |
| metG | cvpA | bbp_103 | bbp_158 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Colicin V production-like protein; COG1286. | 0.442 |
| metG | hisI | bbp_103 | bbp_100 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.612 |
| metG | pheT | bbp_103 | bbp_124 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.970 |
| pheT | cvpA | bbp_124 | bbp_158 | COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Colicin V production-like protein; COG1286. | 0.442 |
| pheT | hisI | bbp_124 | bbp_100 | COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.429 |
| pheT | metG | bbp_124 | bbp_103 | COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.970 |
| purH | cvpA | bbp_032 | bbp_158 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; COG0138; bifunctional purine biosynthesis protein PurH; AICAR transformylase; inosinicase; IMP synthetase; ATIC. | Colicin V production-like protein; COG1286. | 0.456 |