| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argG | asd | bbp_048 | bbp_398 | Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.412 |
| argG | dapA | bbp_048 | bbp_090 | Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.483 |
| argG | lysA | bbp_048 | bbp_388 | Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.641 |
| argG | metF | bbp_048 | bbp_047 | Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 5,10-methylenetetrahydrofolate reductase; COG0685; Belongs to the methylenetetrahydrofolate reductase family. | 0.428 |
| argG | thrA | bbp_048 | bbp_183 | Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartokinase; COG0527; COG0460; bifunctional aspartokinase/homoserine dehydrogenase (AK-HD); In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.965 |
| asd | argG | bbp_398 | bbp_048 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.412 |
| asd | dapA | bbp_398 | bbp_090 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.962 |
| asd | lysA | bbp_398 | bbp_388 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.602 |
| asd | thrA | bbp_398 | bbp_183 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase; COG0527; COG0460; bifunctional aspartokinase/homoserine dehydrogenase (AK-HD); In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.998 |
| asd | thrB | bbp_398 | bbp_182 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.675 |
| asd | thrC | bbp_398 | bbp_181 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.676 |
| cysE | thrA | bbp_051 | bbp_183 | Serine acetyltransferase; COG1045; SAT. | Aspartokinase; COG0527; COG0460; bifunctional aspartokinase/homoserine dehydrogenase (AK-HD); In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.925 |
| cysE | thrB | bbp_051 | bbp_182 | Serine acetyltransferase; COG1045; SAT. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.809 |
| dapA | argG | bbp_090 | bbp_048 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Argininosuccinate synthase; COG0137; citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.483 |
| dapA | asd | bbp_090 | bbp_398 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.962 |
| dapA | lysA | bbp_090 | bbp_388 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.869 |
| dapA | thrA | bbp_090 | bbp_183 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartokinase; COG0527; COG0460; bifunctional aspartokinase/homoserine dehydrogenase (AK-HD); In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.982 |
| ilvH | thrA | bbp_207 | bbp_183 | COG0440; AHAS; acetohydroxy-acid synthase small subunit; ALS. | Aspartokinase; COG0527; COG0460; bifunctional aspartokinase/homoserine dehydrogenase (AK-HD); In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.954 |
| ilvH | thrB | bbp_207 | bbp_182 | COG0440; AHAS; acetohydroxy-acid synthase small subunit; ALS. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.401 |
| ilvH | thrC | bbp_207 | bbp_181 | COG0440; AHAS; acetohydroxy-acid synthase small subunit; ALS. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.474 |