| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsW | ftsY | bbp_199 | bbp_026 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | FtsY protei; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.516 |
| ftsW | yebA | bbp_199 | bbp_296 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | 0.484 |
| ftsY | ftsW | bbp_026 | bbp_199 | FtsY protei; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.516 |
| ftsY | lepB | bbp_026 | bbp_240 | FtsY protei; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | COG0681; SPase I; leader peptidase I; Belongs to the peptidase S26 family. | 0.470 |
| ftsY | yebA | bbp_026 | bbp_296 | FtsY protei; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | 0.673 |
| hflB | htpX | bbp_345 | bbp_299 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Putative protease HtpX; COG0501; heat shock protein HtpX; Belongs to the peptidase M48B family. | 0.935 |
| hflB | lepB | bbp_345 | bbp_240 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | COG0681; SPase I; leader peptidase I; Belongs to the peptidase S26 family. | 0.545 |
| hflB | ptsG | bbp_345 | bbp_326 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | PTS system glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. | 0.776 |
| hflB | yebA | bbp_345 | bbp_296 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | 0.491 |
| htpX | hflB | bbp_299 | bbp_345 | Putative protease HtpX; COG0501; heat shock protein HtpX; Belongs to the peptidase M48B family. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.935 |
| htpX | yebA | bbp_299 | bbp_296 | Putative protease HtpX; COG0501; heat shock protein HtpX; Belongs to the peptidase M48B family. | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | 0.515 |
| lepB | ftsY | bbp_240 | bbp_026 | COG0681; SPase I; leader peptidase I; Belongs to the peptidase S26 family. | FtsY protei; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.470 |
| lepB | hflB | bbp_240 | bbp_345 | COG0681; SPase I; leader peptidase I; Belongs to the peptidase S26 family. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.545 |
| lepB | yebA | bbp_240 | bbp_296 | COG0681; SPase I; leader peptidase I; Belongs to the peptidase S26 family. | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | 0.484 |
| ptsG | hflB | bbp_326 | bbp_345 | PTS system glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.776 |
| ptsG | yebA | bbp_326 | bbp_296 | PTS system glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | 0.633 |
| tyrS | yebA | bbp_115 | bbp_296 | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | 0.476 |
| yebA | ftsW | bbp_296 | bbp_199 | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.484 |
| yebA | ftsY | bbp_296 | bbp_026 | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | FtsY protei; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.673 |
| yebA | hflB | bbp_296 | bbp_345 | Metalloendopeptidases-like membrane protein; COG0739; Belongs to the peptidase M23B family. | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.491 |