| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hisI | murA | bbp_100 | bbp_349 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.684 |
| hisI | rplU | bbp_100 | bbp_350 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.429 |
| hisI | rpmA | bbp_100 | bbp_351 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 50S ribosomal protein L27; COG0211; BL30; BL24; Belongs to the bacterial ribosomal protein bL27 family. | 0.429 |
| hisI | trpD | bbp_100 | bbp_260 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.841 |
| hisI | trpG | bbp_100 | bbp_525 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate synthase component II; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.841 |
| hisI | ydhD | bbp_100 | bbp_176 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | Thioredoxin-like protein 2; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 0.605 |
| hisI | yrbA | bbp_100 | bbp_348 | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | YrbA; COG0271; Belongs to the BolA/IbaG family. | 0.457 |
| murA | hisI | bbp_349 | bbp_100 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.684 |
| murA | rplU | bbp_349 | bbp_350 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.469 |
| murA | rpmA | bbp_349 | bbp_351 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 50S ribosomal protein L27; COG0211; BL30; BL24; Belongs to the bacterial ribosomal protein bL27 family. | 0.525 |
| murA | trpD | bbp_349 | bbp_260 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.447 |
| murA | trpG | bbp_349 | bbp_525 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Anthranilate synthase component II; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.447 |
| murA | yrbA | bbp_349 | bbp_348 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | YrbA; COG0271; Belongs to the BolA/IbaG family. | 0.793 |
| rplU | hisI | bbp_350 | bbp_100 | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.429 |
| rplU | murA | bbp_350 | bbp_349 | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.469 |
| rplU | rpmA | bbp_350 | bbp_351 | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 50S ribosomal protein L27; COG0211; BL30; BL24; Belongs to the bacterial ribosomal protein bL27 family. | 0.999 |
| rplU | yrbA | bbp_350 | bbp_348 | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | YrbA; COG0271; Belongs to the BolA/IbaG family. | 0.409 |
| rpmA | hisI | bbp_351 | bbp_100 | 50S ribosomal protein L27; COG0211; BL30; BL24; Belongs to the bacterial ribosomal protein bL27 family. | phosphoribosyl-AMP cyclohydrolase; COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH; In the C-terminal section; belongs to the PRA-PH family. | 0.429 |
| rpmA | murA | bbp_351 | bbp_349 | 50S ribosomal protein L27; COG0211; BL30; BL24; Belongs to the bacterial ribosomal protein bL27 family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.525 |
| rpmA | rplU | bbp_351 | bbp_350 | 50S ribosomal protein L27; COG0211; BL30; BL24; Belongs to the bacterial ribosomal protein bL27 family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.999 |