typA protein (Buchnera aphidicola Bp) - STRING interaction network

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typA

GTP-binding protein TYPA/BIPA; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily. (616 aa)

Predicted Functional Partners:

polA

0.691

pheA

0.578

engB

0.523

rpmI

0.442

rpsI

0.422

nusA

0.421

infC

0.413

rplA

0.409

Your Current Organism:

Buchnera aphidicola Bp

NCBI taxonomy Id: 224915
Other names: B. aphidicola str. Bp (Baizongia pistaciae), Buchnera aphidicola (subsp. Baizongia pistaciae), Buchnera aphidicola str. Bp (Baizongia pistaciae)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
engB	typA	bbp_383	bbp_384	Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	GTP-binding protein TYPA/BIPA; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.	0.523
infC	pheA	bbp_120	bbp_355	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	0.476
infC	polA	bbp_120	bbp_382	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	Putative 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.	0.780
infC	rplA	bbp_120	bbp_038	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.925
infC	rpmI	bbp_120	bbp_121	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	COG0291; ribosomal protein A; Belongs to the bacterial ribosomal protein bL35 family.	0.989
infC	rpsI	bbp_120	bbp_353	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	Ribosomal protein S9; COG0103; BS10; Belongs to the universal ribosomal protein uS9 family.	0.954
infC	typA	bbp_120	bbp_384	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GTP-binding protein TYPA/BIPA; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.	0.413
nusA	pheA	bbp_341	bbp_355	N utilization substance protein A; Participates in both transcription termination and antitermination.	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	0.513
nusA	polA	bbp_341	bbp_382	N utilization substance protein A; Participates in both transcription termination and antitermination.	Putative 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.	0.576
nusA	rplA	bbp_341	bbp_038	N utilization substance protein A; Participates in both transcription termination and antitermination.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.976
nusA	rpmI	bbp_341	bbp_121	N utilization substance protein A; Participates in both transcription termination and antitermination.	COG0291; ribosomal protein A; Belongs to the bacterial ribosomal protein bL35 family.	0.796
nusA	rpsI	bbp_341	bbp_353	N utilization substance protein A; Participates in both transcription termination and antitermination.	Ribosomal protein S9; COG0103; BS10; Belongs to the universal ribosomal protein uS9 family.	0.794
nusA	typA	bbp_341	bbp_384	N utilization substance protein A; Participates in both transcription termination and antitermination.	GTP-binding protein TYPA/BIPA; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.	0.421
pheA	infC	bbp_355	bbp_120	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.476
pheA	nusA	bbp_355	bbp_341	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	N utilization substance protein A; Participates in both transcription termination and antitermination.	0.513
pheA	polA	bbp_355	bbp_382	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	Putative 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.	0.478
pheA	rpmI	bbp_355	bbp_121	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	COG0291; ribosomal protein A; Belongs to the bacterial ribosomal protein bL35 family.	0.476
pheA	rpsI	bbp_355	bbp_353	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	Ribosomal protein S9; COG0103; BS10; Belongs to the universal ribosomal protein uS9 family.	0.467
pheA	typA	bbp_355	bbp_384	P-protein; Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.	GTP-binding protein TYPA/BIPA; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.	0.578
polA	infC	bbp_382	bbp_120	Putative 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.780

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