| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cca | yggX | bbp_057 | bbp_501 | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.538 |
| murI | mutY | bbp_502 | bbp_500 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo- dGTP); Belongs to the Nth/MutY family. | 0.572 |
| murI | yggH | bbp_502 | bbp_499 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Hypothetical methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.410 |
| murI | yggX | bbp_502 | bbp_501 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.570 |
| mutY | murI | bbp_500 | bbp_502 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo- dGTP); Belongs to the Nth/MutY family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.572 |
| mutY | yggH | bbp_500 | bbp_499 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo- dGTP); Belongs to the Nth/MutY family. | Hypothetical methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.618 |
| mutY | yggX | bbp_500 | bbp_501 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo- dGTP); Belongs to the Nth/MutY family. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.837 |
| ygfZ | yggX | bbp_391 | bbp_501 | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.549 |
| yggH | murI | bbp_499 | bbp_502 | Hypothetical methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.410 |
| yggH | mutY | bbp_499 | bbp_500 | Hypothetical methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo- dGTP); Belongs to the Nth/MutY family. | 0.618 |
| yggH | yggX | bbp_499 | bbp_501 | Hypothetical methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.615 |
| yggX | cca | bbp_501 | bbp_057 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily. | 0.538 |
| yggX | murI | bbp_501 | bbp_502 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.570 |
| yggX | mutY | bbp_501 | bbp_500 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo- dGTP); Belongs to the Nth/MutY family. | 0.837 |
| yggX | ygfZ | bbp_501 | bbp_391 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.549 |
| yggX | yggH | bbp_501 | bbp_499 | Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Hypothetical methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.615 |
