STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfBUnannotated protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (285 aa)    
Predicted Functional Partners:
rplU
Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.984
rpsP
Unannotated protein; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.982
rpmA
Unannotated protein; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.979
rplM
Unannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.975
rpsG
Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
 
 
 0.975
rplD
Unannotated protein; Forms part of the polypeptide exit tunnel.
  
 
 0.974
rpsL
Unannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 
 0.971
rplQ
Unannotated protein.
  
   0.969
rpmJ
Unannotated protein; Belongs to the bacterial ribosomal protein bL36 family.
   
 
 0.967
rplX
Unannotated protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
   0.963
Your Current Organism:
Tepidanaerobacter syntrophicus
NCBI taxonomy Id: 224999
Other names: DSM 15584, JCM 12098, NBRC 100060, T. syntrophicus, Tepidanaerobacter syntrophicus Sekiguchi et al. 2006, anaerobic syntrophic bacterium JE, anaerobic syntrophic bacterium JL, anaerobic syntrophic bacterium OL, strain JL
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.