STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4A064_LOTGIPWWP domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (1244 aa)    
Predicted Functional Partners:
V3ZN41_LOTGI
DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
V4B982_LOTGI
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.998
V4B6C5_LOTGI
Uncharacterized protein.
 
 0.992
V3Z9S6_LOTGI
Uncharacterized protein.
   
 0.983
V4C485_LOTGI
DNA_mis_repair domain-containing protein.
 
 0.977
V4B4P5_LOTGI
DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 
 
0.958
V4B1I5_LOTGI
Uncharacterized protein.
 
 0.950
V4AKB4_LOTGI
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.929
V4A877_LOTGI
Uncharacterized protein.
  
 0.920
V4ASC3_LOTGI
DNA_mis_repair domain-containing protein.
  
 0.920
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.