STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4A783_LOTGIHistone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa)    
Predicted Functional Partners:
V4BKR5_LOTGI
WD_REPEATS_REGION domain-containing protein.
   
 0.922
V4ANE5_LOTGI
HDAC_interact domain-containing protein.
   
 0.921
V4BLS6_LOTGI
Uncharacterized protein.
   
 0.910
V4AIZ9_LOTGI
Uncharacterized protein.
    
 0.898
V4A8I8_LOTGI
Uncharacterized protein.
   
 0.888
V4C835_LOTGI
SANT domain-containing protein.
    
 0.879
V4CJ94_LOTGI
Uncharacterized protein.
    
 0.868
V4ANA8_LOTGI
MRG domain-containing protein.
   
 0.847
V3ZE46_LOTGI
Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.
   
 0.836
V4CEX9_LOTGI
MBD domain-containing protein.
    
 0.814
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.