STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4A7K8_LOTGIUbiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (168 aa)    
Predicted Functional Partners:
V3ZPW0_LOTGI
ThiF domain-containing protein.
  
 
 
 0.963
V3ZH76_LOTGI
Uncharacterized protein.
   
 
 0.903
V4BL95_LOTGI
Uncharacterized protein.
    
 
 0.779
V4AXQ4_LOTGI
Uncharacterized protein.
    
 
 0.761
V4A6P5_LOTGI
Uncharacterized protein.
   
  
 0.682
V4A9A1_LOTGI
Uncharacterized protein.
  
  
 0.664
V3ZM40_LOTGI
Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...]
    
 
 0.642
V4AFS3_LOTGI
Uncharacterized protein.
   
 
 0.570
V4C2X0_LOTGI
E2_bind domain-containing protein.
    
 
 0.525
V3ZQN4_LOTGI
ThiF domain-containing protein.
    
 
 0.487
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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