STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4ABN5_LOTGIUncharacterized protein; Belongs to the BI1 family. (236 aa)    
Predicted Functional Partners:
V4BA95_LOTGI
DUF862 domain-containing protein.
    
   0.915
V3ZWW7_LOTGI
DUF862 domain-containing protein.
    
   0.674
V4B908_LOTGI
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.664
V4A7K9_LOTGI
Uncharacterized protein; Belongs to the BI1 family.
   
  
0.654
V4AGU0_LOTGI
Uncharacterized protein.
      
 0.597
V4AF59_LOTGI
Protein-L-isoaspartate O-methyltransferase.
      
 0.571
V4ATJ4_LOTGI
Uncharacterized protein.
      
 0.540
V4A654_LOTGI
AAA domain-containing protein.
      
 0.527
V4BB49_LOTGI
Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]
      
 0.523
V4A6B7_LOTGI
Prohibitin.
    
 
 0.487
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.