STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4AMH9_LOTGIHMG box domain-containing protein. (448 aa)    
Predicted Functional Partners:
V3ZE46_LOTGI
Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.
   
 0.724
V4AC70_LOTGI
Uncharacterized protein.
   
 0.659
V3YX11_LOTGI
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.653
V4AEJ9_LOTGI
PHD-type domain-containing protein.
    
 0.652
V3ZRI6_LOTGI
Uncharacterized protein.
    
 0.627
V4A0H2_LOTGI
Uncharacterized protein.
    
 0.613
V4CQ04_LOTGI
Uncharacterized protein; Belongs to the actin family.
    
 0.612
V4B2S3_LOTGI
Uncharacterized protein; Belongs to the actin family.
   
 0.611
V4AYE4_LOTGI
RuvB-like helicase; Belongs to the RuvB family.
    
 0.610
V4BAV0_LOTGI
Uncharacterized protein.
   
 0.610
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.