STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4AN55_LOTGIUSP domain-containing protein. (219 aa)    
Predicted Functional Partners:
V3ZN23_LOTGI
Uncharacterized protein.
    
 0.680
V3ZS69_LOTGI
Uncharacterized protein.
    
 0.680
V3ZUT2_LOTGI
Small ubiquitin-related modifier.
    
 0.679
V3ZX92_LOTGI
Uncharacterized protein.
   
 0.547
V4BEP5_LOTGI
NARG2_C domain-containing protein.
   
  
 0.545
V4BA95_LOTGI
DUF862 domain-containing protein.
      
 0.541
V4AVC2_LOTGI
Uncharacterized protein.
    
 0.478
PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...]
    
 
 0.474
V4B961_LOTGI
Ubiquitin carboxyl-terminal hydrolase.
      
 0.470
V3ZVT0_LOTGI
WD_REPEATS_REGION domain-containing protein.
      
 0.469
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.