STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4BEI5_LOTGIDNA polymerase. (881 aa)    
Predicted Functional Partners:
V3ZXE7_LOTGI
DNA_pol_B_exo1 domain-containing protein.
 
  
  0.991
V3ZXA1_LOTGI
Uncharacterized protein.
   
 0.972
V3ZHD3_LOTGI
HORMA domain-containing protein.
    
 0.965
V4AK20_LOTGI
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
   
 0.965
V3ZYD5_LOTGI
Uncharacterized protein.
   
 0.949
V4BFG0_LOTGI
ERCC4 domain-containing protein.
   
 0.949
V4B982_LOTGI
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.930
V4A559_LOTGI
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 0.906
V4BAC9_LOTGI
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.887
V3Z1P4_LOTGI
UmuC domain-containing protein.
   
 0.884
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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