STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4BEL3_LOTGIPPM-type phosphatase domain-containing protein. (357 aa)    
Predicted Functional Partners:
V4BVZ4_LOTGI
Transket_pyr domain-containing protein.
   
 0.834
V4AC07_LOTGI
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.780
V4AHL2_LOTGI
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.654
V4BY99_LOTGI
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.654
V4BHZ2_LOTGI
Uncharacterized protein.
   
 0.542
V3ZU39_LOTGI
MSP domain-containing protein.
    
 0.526
V4A6K4_LOTGI
Dihydrolipoyl dehydrogenase.
   
 0.499
V3ZEY7_LOTGI
Uncharacterized protein.
  
   0.453
V4BE97_LOTGI
RanBP2-type domain-containing protein.
    
 0.451
V4AIS1_LOTGI
Uncharacterized protein.
   
 0.439
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.