node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SJZ32688.1 | SJZ38081.1 | SAMN02745126_00375 | SAMN02745126_00763 | Glutamate synthase (NADH) large subunit. | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | 0.900 |
SJZ32688.1 | SJZ56155.1 | SAMN02745126_00375 | SAMN02745126_01632 | Glutamate synthase (NADH) large subunit. | 4-methylaminobutanoate oxidase (formaldehyde-forming); Belongs to the GcvT family. | 0.932 |
SJZ32688.1 | SJZ80155.1 | SAMN02745126_00375 | SAMN02745126_02344 | Glutamate synthase (NADH) large subunit. | Dihydrolipoamide dehydrogenase. | 0.892 |
SJZ32688.1 | SJZ81530.1 | SAMN02745126_00375 | SAMN02745126_02395 | Glutamate synthase (NADH) large subunit. | Glycine dehydrogenase subunit 2. | 0.901 |
SJZ32688.1 | SJZ92193.1 | SAMN02745126_00375 | SAMN02745126_02882 | Glutamate synthase (NADH) large subunit. | Glutamate synthase (NADPH/NADH) large chain. | 0.999 |
SJZ32688.1 | SKA16142.1 | SAMN02745126_00375 | SAMN02745126_03861 | Glutamate synthase (NADH) large subunit. | Thioredoxin reductase. | 0.925 |
SJZ32688.1 | folD | SAMN02745126_00375 | SAMN02745126_03113 | Glutamate synthase (NADH) large subunit. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.452 |
SJZ32688.1 | gcvH | SAMN02745126_00375 | SAMN02745126_02397 | Glutamate synthase (NADH) large subunit. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.888 |
SJZ32688.1 | gcvPA | SAMN02745126_00375 | SAMN02745126_02396 | Glutamate synthase (NADH) large subunit. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.891 |
SJZ32688.1 | glyA | SAMN02745126_00375 | SAMN02745126_01492 | Glutamate synthase (NADH) large subunit. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.897 |
SJZ38081.1 | SJZ32688.1 | SAMN02745126_00763 | SAMN02745126_00375 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Glutamate synthase (NADH) large subunit. | 0.900 |
SJZ38081.1 | SJZ56155.1 | SAMN02745126_00763 | SAMN02745126_01632 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | 4-methylaminobutanoate oxidase (formaldehyde-forming); Belongs to the GcvT family. | 0.940 |
SJZ38081.1 | SJZ80155.1 | SAMN02745126_00763 | SAMN02745126_02344 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Dihydrolipoamide dehydrogenase. | 0.856 |
SJZ38081.1 | SJZ81530.1 | SAMN02745126_00763 | SAMN02745126_02395 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Glycine dehydrogenase subunit 2. | 0.685 |
SJZ38081.1 | SJZ92193.1 | SAMN02745126_00763 | SAMN02745126_02882 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Glutamate synthase (NADPH/NADH) large chain. | 0.900 |
SJZ38081.1 | SKA16142.1 | SAMN02745126_00763 | SAMN02745126_03861 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Thioredoxin reductase. | 0.452 |
SJZ38081.1 | folD | SAMN02745126_00763 | SAMN02745126_03113 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.400 |
SJZ38081.1 | gcvH | SAMN02745126_00763 | SAMN02745126_02397 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.427 |
SJZ38081.1 | gcvPA | SAMN02745126_00763 | SAMN02745126_02396 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.655 |
SJZ38081.1 | glyA | SAMN02745126_00763 | SAMN02745126_01492 | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.710 |