Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
macA_1Macrolide export protein MacA. (473 aa)    
Predicted Functional Partners:
macB_1
Macrolide export ATP-binding/permease protein MacB.
 
  
 0.976
lolD_1
Lipoprotein-releasing system ATP-binding protein LolD.
 
  
 0.937
macB_5
Macrolide export ATP-binding/permease protein MacB.
 
  
 0.874
macB_6
Macrolide export ATP-binding/permease protein MacB.
 
  
 0.735
macB_4
Macrolide export ATP-binding/permease protein MacB.
 
  
 0.733
OPJ66241.1
Outer membrane efflux protein.
  
 0.731
OPJ65930.1
Outer membrane efflux protein.
  
 0.731
OPJ65946.1
Hypothetical protein.
  
 0.731
OPJ65298.1
Hypothetical protein.
  
 0.731
OPJ62353.1
Outer membrane efflux protein.
  
 0.731
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
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