Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mccBCystathionine gamma-lyase. (382 aa)    
Predicted Functional Partners:
yitJ
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
  
 0.979
mccA
O-acetylserine dependent cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.894
metH_1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.892
metH_2
Methionine synthase.
  
 
 0.892
cdr_2
Coenzyme A disulfide reductase; Belongs to the sulfur carrier protein TusA family.
  
 
 0.866
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.864
nifJ_3
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.864
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.844
cysK1
O-acetylserine sulfhydrylase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.844
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
    
 0.841
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
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