Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sigMRNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa)    
Predicted Functional Partners:
OPJ65597.1
Hypothetical protein.
 
     0.900
OPJ65598.1
Hypothetical protein.
       0.839
OPJ65596.1
Hypothetical protein.
  
  
 0.793
sigW_3
ECF RNA polymerase sigma factor SigW; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.706
sigW_2
ECF RNA polymerase sigma factor SigW; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.704
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.685
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.677
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.667
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.628
sigJ
ECF RNA polymerase sigma factor SigJ; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.618
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
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