Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pflA_1Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (236 aa)    
Predicted Functional Partners:
pflB_1
Formate acetyltransferase.
 
 0.971
pflB_2
Formate acetyltransferase.
 
 0.971
bssA_1
Benzylsuccinate synthase alpha subunit.
 
 
 0.907
bssA_2
Benzylsuccinate synthase alpha subunit.
 
 
 0.875
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU.
   
    0.822
crp_2
cAMP receptor protein.
    
 0.787
adhE_1
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.719
adhE_3
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.719
mdh_1
NAD-dependent methanol dehydrogenase.
  
 
 0.609
dhaT_1
1,3-propanediol dehydrogenase.
  
 
 0.609
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
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