Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hflKModulator of FtsH protease HflK. (314 aa)    
Predicted Functional Partners:
OPJ65318.1
Hypothetical protein; NfeD-like C-terminal, partner-binding.
 
 
 0.990
ftsH_1
ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.862
ftsH_2
ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.862
ftsH_3
ATP-dependent zinc metalloprotease FtsH; Belongs to the AAA ATPase family.
   
 0.862
ftsH_4
ATP-dependent zinc metalloprotease FtsH.
   
 0.862
gluP
Rhomboid protease GluP.
   
 0.836
misCA
Membrane protein insertase MisCA precursor.
  
 
 0.806
ptrA_1
Protease 3 precursor; Belongs to the peptidase M16 family.
  
 0.760
ptrA_2
Protease 3 precursor; Belongs to the peptidase M16 family.
  
 0.760
OPJ61269.1
Insulinase.
  
 0.760
Your Current Organism:
Clostridium chromiireducens
NCBI taxonomy Id: 225345
Other names: C. chromiireducens, Clostridium chromiireducens Inglett et al. 2011, DSM 23318, KCTC 5935, strain GCAF-1
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